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3b6u
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==Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP== | ==Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP== | ||
| - | <StructureSection load='3b6u' size='340' side='right' caption='[[3b6u]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='3b6u' size='340' side='right'caption='[[3b6u]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3b6u]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3b6u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B6U FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6u OCA], [https://pdbe.org/3b6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b6u RCSB], [https://www.ebi.ac.uk/pdbsum/3b6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b6u ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/KIF3B_HUMAN KIF3B_HUMAN] Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6u_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6u_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
| - | *[[Kinesin|Kinesin]] | + | *[[Kinesin 3D Structures|Kinesin 3D Structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bochkarev | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Edwards | + | [[Category: Bochkarev A]] |
| - | [[Category: Landry | + | [[Category: Edwards AM]] |
| - | [[Category: Park | + | [[Category: Landry R]] |
| - | + | [[Category: Park H]] | |
| - | [[Category: Shen | + | [[Category: Shen Y]] |
| - | [[Category: Sundstrom | + | [[Category: Sundstrom M]] |
| - | [[Category: Tempel | + | [[Category: Tempel W]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Zhu | + | [[Category: Zhu H]] |
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Current revision
Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Edwards AM | Landry R | Park H | Shen Y | Sundstrom M | Tempel W | Weigelt J | Zhu H
