1tq1

From Proteopedia

(Difference between revisions)

Current revision

Solution structure of At5g66040, a putative protein from Arabidosis Thaliana

Structural highlights

1tq1 is a 1 chain structure with sequence from Arabidopsis thaliana. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

STR16_ARATH Thought to act during the early stages of leaf senescence. Catalyzes the transfer of a sulfur ion from a donor to cyanide or to other thiol compounds. Substrate preference is thiosulfate > 3-mercaptopyruvate.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

We describe the three-dimensional structure of the product of Arabidopsis thaliana gene At5g66040.1 as determined by NMR spectroscopy. This protein is categorized as single-domain sulfurtransferase and is annotated as a senescence-associated protein (sen1-like protein) and ketoconazole resistance protein (http://arabidopsis.org/info/genefamily/STR_genefamily.html). The sequence of At5g66040.1 is virtually identical to that of a protein from Arabidopsis found by others to confer ketoconazole resistance in yeast. Comparison of the three-dimensional structure with those in the Protein Data Bank revealed that At5g66040.1 contains an additional mobile beta-hairpin not found in other rhodaneses that may function in binding specific substrates. This represents the first structure of a single-domain plant sulfurtransferase. The enzymatically active cysteine-containing domain belongs to the CDC25 class of phosphatases, sulfide dehydrogenases, and stress proteins such as senescence specific protein 1 in plants, PspE and GlpE in bacteria, and cyanide and arsenate resistance proteins. Versions of this domain that lack the active site cysteine are found in other proteins, such as phosphatases, ubiquitin hydrolases, and sulfuryltransferases.

Solution structure of a single-domain thiosulfate sulfurtransferase from Arabidopsis thaliana.,Cornilescu G, Vinarov DA, Tyler EM, Markley JL, Cornilescu CC Protein Sci. 2006 Dec;15(12):2836-41. Epub 2006 Nov 6. PMID:17088324^[2]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Bauer M, Papenbrock J. Identification and characterization of single-domain thiosulfate sulfurtransferases from Arabidopsis thaliana. FEBS Lett. 2002 Dec 18;532(3):427-31. PMID:12482606
↑ Cornilescu G, Vinarov DA, Tyler EM, Markley JL, Cornilescu CC. Solution structure of a single-domain thiosulfate sulfurtransferase from Arabidopsis thaliana. Protein Sci. 2006 Dec;15(12):2836-41. Epub 2006 Nov 6. PMID:17088324 doi:10.1110/ps.062395206

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1tq1"

@@ Line 1: / Line 1: @@
 ==Solution structure of At5g66040, a putative protein from Arabidosis Thaliana==
-<StructureSection load='1tq1' size='340' side='right' caption='[[1tq1]], [[NMR_Ensembles_of_Models | 5 NMR models]]' scene=''>
+<StructureSection load='1tq1' size='340' side='right'caption='[[1tq1]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1tq1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TQ1 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1tq1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TQ1 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tq1 OCA], [http://pdbe.org/1tq1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tq1 RCSB], [http://www.ebi.ac.uk/pdbsum/1tq1 PDBsum], [http://www.topsan.org/Proteins/CESG/1tq1 TOPSAN]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tq1 OCA], [https://pdbe.org/1tq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tq1 RCSB], [https://www.ebi.ac.uk/pdbsum/1tq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tq1 ProSAT], [https://www.topsan.org/Proteins/CESG/1tq1 TOPSAN]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/STR16_ARATH STR16_ARATH]] Thought to act during the early stages of leaf senescence. Catalyzes the transfer of a sulfur ion from a donor to cyanide or to other thiol compounds. Substrate preference is thiosulfate > 3-mercaptopyruvate.<ref>PMID:12482606</ref>
+[https://www.uniprot.org/uniprot/STR16_ARATH STR16_ARATH] Thought to act during the early stages of leaf senescence. Catalyzes the transfer of a sulfur ion from a donor to cyanide or to other thiol compounds. Substrate preference is thiosulfate > 3-mercaptopyruvate.<ref>PMID:12482606</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
   <jmolCheckbox>
-    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tq/1tq1_consurf.spt"</scriptWhenChecked>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tq/1tq1_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 30: / Line 32: @@
 __TOC__
 </StructureSection>
-[[Category: Arath]]
+[[Category: Arabidopsis thaliana]]
-[[Category: Structural genomic]]
+[[Category: Large Structures]]
-[[Category: Cornilescu, C C]]
+[[Category: Cornilescu CC]]
-[[Category: Cornilescu, G]]
+[[Category: Cornilescu G]]
-[[Category: Lee, M S]]
+[[Category: Lee MS]]
-[[Category: Markley, J L]]
+[[Category: Markley JL]]
-[[Category: Shahan, M N]]
+[[Category: Shahan MN]]
-[[Category: Singh, S]]
+[[Category: Singh S]]
-[[Category: Tyler, E M]]
+[[Category: Tyler EM]]
-[[Category: Vinarov, D]]
+[[Category: Vinarov D]]
-[[Category: At5g66040]]
-[[Category: Cesg]]
-[[Category: PSI, Protein structure initiative]]
-[[Category: Unknown function]]

1tq1

From Proteopedia

Current revision

Solution structure of At5g66040, a putative protein from Arabidosis Thaliana

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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