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1qn7
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='1qn7' size='340' side='right' caption='[[1qn7]], [[Resolution|resolution]] 2.30Å' scene=''> | + | ==Crystal structure of the T(-27) Adenovirus major late promoter TATA box variant bound to wild-type TBP (Arabidopsis thaliana TBP isoform 2). TATA element recognition by the TATA box-binding protein has been conserved throughout evolution.== |
| + | <StructureSection load='1qn7' size='340' side='right'caption='[[1qn7]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1qn7]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1qn7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QN7 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qn7 OCA], [https://pdbe.org/1qn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qn7 RCSB], [https://www.ebi.ac.uk/pdbsum/1qn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qn7 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TBP1_ARATH TBP1_ARATH] General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/1qn7_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/1qn7_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
| - | *[[TATA- | + | *[[TATA-binding protein 3D structures|TATA-binding protein 3D structures]] |
| - | *[[Transcription initiation | + | *[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Arabidopsis thaliana]] |
| - | [[Category: Burley | + | [[Category: Large Structures]] |
| - | [[Category: Kim | + | [[Category: Burley SK]] |
| - | [[Category: Kodadek | + | [[Category: Kim JL]] |
| - | [[Category: Patikoglou | + | [[Category: Kodadek T]] |
| - | [[Category: Sun | + | [[Category: Patikoglou GA]] |
| - | [[Category: Yang | + | [[Category: Sun L]] |
| - | + | [[Category: Yang S-H]] | |
Current revision
Crystal structure of the T(-27) Adenovirus major late promoter TATA box variant bound to wild-type TBP (Arabidopsis thaliana TBP isoform 2). TATA element recognition by the TATA box-binding protein has been conserved throughout evolution.
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