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2dlt

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==Solution structure of the Ig-like domain(433- 525) of murine myosin-binding protein C, fast-type==
==Solution structure of the Ig-like domain(433- 525) of murine myosin-binding protein C, fast-type==
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<StructureSection load='2dlt' size='340' side='right' caption='[[2dlt]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dlt' size='340' side='right'caption='[[2dlt]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dlt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DLT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DLT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dlt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DLT FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mybpc2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dlt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dlt OCA], [http://pdbe.org/2dlt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dlt RCSB], [http://www.ebi.ac.uk/pdbsum/2dlt PDBsum], [http://www.topsan.org/Proteins/RSGI/2dlt TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dlt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dlt OCA], [https://pdbe.org/2dlt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dlt RCSB], [https://www.ebi.ac.uk/pdbsum/2dlt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dlt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dlt TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MYPC2_MOUSE MYPC2_MOUSE]] Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role (By similarity).
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[https://www.uniprot.org/uniprot/MYPC2_MOUSE MYPC2_MOUSE] Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/2dlt_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/2dlt_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Hayashi, F]]
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[[Category: Mus musculus]]
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[[Category: Inoue, K]]
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[[Category: Hayashi F]]
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[[Category: Izumi, K]]
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[[Category: Inoue K]]
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[[Category: Structural genomic]]
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[[Category: Izumi K]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Yoshida, M]]
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[[Category: Yoshida M]]
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[[Category: Contractile protein]]
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[[Category: Fast-type]]
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[[Category: Ig-like domain]]
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[[Category: Mybpc2]]
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[[Category: Myosin binding protein c]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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Current revision

Solution structure of the Ig-like domain(433- 525) of murine myosin-binding protein C, fast-type

PDB ID 2dlt

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