2qdk

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==X-ray structure of the unliganded uridine phosphorylase from Salmonella typhimurium at 1.62A resolution==
==X-ray structure of the unliganded uridine phosphorylase from Salmonella typhimurium at 1.62A resolution==
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<StructureSection load='2qdk' size='340' side='right' caption='[[2qdk]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
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<StructureSection load='2qdk' size='340' side='right'caption='[[2qdk]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qdk]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QDK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qdk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QDK FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">udp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qdk OCA], [https://pdbe.org/2qdk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qdk RCSB], [https://www.ebi.ac.uk/pdbsum/2qdk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qdk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qdk OCA], [http://pdbe.org/2qdk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qdk RCSB], [http://www.ebi.ac.uk/pdbsum/2qdk PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY]] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
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[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/2qdk_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/2qdk_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Uridine phosphorylase|Uridine phosphorylase]]
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*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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[[Category: Large Structures]]
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[[Category: Uridine phosphorylase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Gabdoulkhakov, A G]]
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[[Category: Gabdoulkhakov AG]]
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[[Category: Lashkov, A A]]
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[[Category: Lashkov AA]]
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[[Category: Mikhailov, A M]]
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[[Category: Mikhailov AM]]
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[[Category: Pavlyuk, B P]]
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[[Category: Pavlyuk BP]]
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[[Category: Timofeev, V I]]
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[[Category: Timofeev VI]]
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[[Category: Nucleoside phosphorylase]]
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[[Category: Transferase]]
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Current revision

X-ray structure of the unliganded uridine phosphorylase from Salmonella typhimurium at 1.62A resolution

PDB ID 2qdk

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