2q9v
From Proteopedia
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==Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase== | ==Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase== | ||
| - | <StructureSection load='2q9v' size='340' side='right' caption='[[2q9v]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='2q9v' size='340' side='right'caption='[[2q9v]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2q9v]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2q9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q9V FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q9v OCA], [https://pdbe.org/2q9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q9v RCSB], [https://www.ebi.ac.uk/pdbsum/2q9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q9v ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/2q9v_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/2q9v_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
| - | *[[Guanylate kinase|Guanylate kinase]] | + | *[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CA]] |
| - | [[Category: | + | [[Category: Cooper C]] |
| - | [[Category: Doyle | + | [[Category: Doyle DA]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Elkins | + | [[Category: Elkins JM]] |
| - | [[Category: Hozjan | + | [[Category: Hozjan V]] |
| - | [[Category: Kavanagh | + | [[Category: Kavanagh KL]] |
| - | [[Category: Oppermann | + | [[Category: Oppermann U]] |
| - | [[Category: Papagrigoriou | + | [[Category: Papagrigoriou E]] |
| - | [[Category: Pilka | + | [[Category: Pilka ES]] |
| - | + | [[Category: Sundstrom M]] | |
| - | [[Category: Sundstrom | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
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Current revision
Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase
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Categories: Homo sapiens | Large Structures | Arrowsmith CA | Cooper C | Doyle DA | Edwards A | Elkins JM | Hozjan V | Kavanagh KL | Oppermann U | Papagrigoriou E | Pilka ES | Sundstrom M | Weigelt J | Von Delft F
