This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1zow

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:12, 23 August 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal Structure of S. aureus FabH, beta-ketoacyl carrier protein synthase III==
==Crystal Structure of S. aureus FabH, beta-ketoacyl carrier protein synthase III==
-
<StructureSection load='1zow' size='340' side='right' caption='[[1zow]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+
<StructureSection load='1zow' size='340' side='right'caption='[[1zow]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1zow]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staaw Staaw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZOW FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1zow]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZOW FirstGlance]. <br>
-
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_I Beta-ketoacyl-[acyl-carrier-protein] synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zow OCA], [http://pdbe.org/1zow PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zow RCSB], [http://www.ebi.ac.uk/pdbsum/1zow PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zow OCA], [https://pdbe.org/1zow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zow RCSB], [https://www.ebi.ac.uk/pdbsum/1zow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zow ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/FABH_STAAW FABH_STAAW]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids (By similarity).
+
[https://www.uniprot.org/uniprot/FABH_STAAW FABH_STAAW] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/1zow_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/1zow_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 29: Line 30:
==See Also==
==See Also==
-
*[[Acyl carrier protein synthase|Acyl carrier protein synthase]]
+
*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Staaw]]
+
[[Category: Large Structures]]
-
[[Category: Choudhry, A E]]
+
[[Category: Staphylococcus aureus subsp. aureus MW2]]
-
[[Category: Daines, R A]]
+
[[Category: Choudhry AE]]
-
[[Category: Grooms, M]]
+
[[Category: Daines RA]]
-
[[Category: Janson, C A]]
+
[[Category: Grooms M]]
-
[[Category: Khandekar, S S]]
+
[[Category: Janson CA]]
-
[[Category: Lonsdale, J T]]
+
[[Category: Khandekar SS]]
-
[[Category: Qiu, X]]
+
[[Category: Lonsdale JT]]
-
[[Category: Fabh]]
+
[[Category: Qiu X]]
-
[[Category: Fatty acid biosynthesis]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal Structure of S. aureus FabH, beta-ketoacyl carrier protein synthase III

PDB ID 1zow

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1zow"
Personal tools