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3iql

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==Crystal structure of the rat endophilin-A1 SH3 domain==
==Crystal structure of the rat endophilin-A1 SH3 domain==
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<StructureSection load='3iql' size='340' side='right' caption='[[3iql]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='3iql' size='340' side='right'caption='[[3iql]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3iql]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IQL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IQL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3iql]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IQL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2knb|2knb]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sh3d2a, Sh3gl2, Sh3p4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iql OCA], [https://pdbe.org/3iql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iql RCSB], [https://www.ebi.ac.uk/pdbsum/3iql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iql ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iql OCA], [http://pdbe.org/3iql PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iql RCSB], [http://www.ebi.ac.uk/pdbsum/3iql PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SH3G2_RAT SH3G2_RAT]] Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.<ref>PMID:11604418</ref> <ref>PMID:16763559</ref>
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[https://www.uniprot.org/uniprot/SH3G2_RAT SH3G2_RAT] Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.<ref>PMID:11604418</ref> <ref>PMID:16763559</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/3iql_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/3iql_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
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[[Category: Large Structures]]
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[[Category: Camacho, E M]]
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[[Category: Rattus norvegicus]]
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[[Category: Gehring, K]]
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[[Category: Camacho EM]]
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[[Category: Kozlov, G]]
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[[Category: Gehring K]]
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[[Category: Trempe, J F]]
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[[Category: Kozlov G]]
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[[Category: Endocytosis]]
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[[Category: Trempe JF]]
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[[Category: Endophilin]]
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[[Category: Lipid-binding]]
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[[Category: Membrane]]
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[[Category: Phosphoprotein]]
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[[Category: Protein binding]]
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[[Category: Sh3]]
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[[Category: Sh3 domain]]
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Current revision

Crystal structure of the rat endophilin-A1 SH3 domain

PDB ID 3iql

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