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2ihc
From Proteopedia
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==Crystal structure of the bric-a-brac (BTB) domain of human BACH1== | ==Crystal structure of the bric-a-brac (BTB) domain of human BACH1== | ||
| - | <StructureSection load='2ihc' size='340' side='right' caption='[[2ihc]], [[Resolution|resolution]] 2.44Å' scene=''> | + | <StructureSection load='2ihc' size='340' side='right'caption='[[2ihc]], [[Resolution|resolution]] 2.44Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ihc]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ihc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IHC FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.44Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ihc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ihc OCA], [https://pdbe.org/2ihc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ihc RCSB], [https://www.ebi.ac.uk/pdbsum/2ihc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ihc ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BACH1_HUMAN BACH1_HUMAN] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/2ihc_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/2ihc_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Amos | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Amos AL]] |
| - | [[Category: Bullock | + | [[Category: Arrowsmith C]] |
| - | [[Category: Bunkoczi | + | [[Category: Bullock A]] |
| - | + | [[Category: Bunkoczi G]] | |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Gorrec | + | [[Category: Gorrec F]] |
| - | [[Category: Knapp | + | [[Category: Knapp S]] |
| - | [[Category: Papagrigoriou | + | [[Category: Papagrigoriou E]] |
| - | + | [[Category: Sundstrom M]] | |
| - | [[Category: Sundstrom | + | [[Category: Turnbull AP]] |
| - | [[Category: Turnbull | + | [[Category: Umeano C]] |
| - | [[Category: Umeano | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
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Current revision
Crystal structure of the bric-a-brac (BTB) domain of human BACH1
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Categories: Homo sapiens | Large Structures | Amos AL | Arrowsmith C | Bullock A | Bunkoczi G | Edwards A | Gorrec F | Knapp S | Papagrigoriou E | Sundstrom M | Turnbull AP | Umeano C | Weigelt J | Von Delft F
