3d9s
From Proteopedia
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==Human Aquaporin 5 (AQP5) - High Resolution X-ray Structure== | ==Human Aquaporin 5 (AQP5) - High Resolution X-ray Structure== | ||
- | <StructureSection load='3d9s' size='340' side='right' caption='[[3d9s]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='3d9s' size='340' side='right'caption='[[3d9s]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3d9s]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3d9s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D9S FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PS6:O-[(S)-{[(2S)-2-(HEXANOYLOXY)-3-(TETRADECANOYLOXY)PROPYL]OXY}(HYDROXY)PHOSPHORYL]-D-SERINE'>PS6</scene></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9s OCA], [https://pdbe.org/3d9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9s RCSB], [https://www.ebi.ac.uk/pdbsum/3d9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9s ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/AQP5_HUMAN AQP5_HUMAN] Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/3d9s_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/3d9s_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
- | *[[Aquaporin|Aquaporin]] | + | *[[Aquaporin 3D structures|Aquaporin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: Backmark | + | [[Category: Large Structures]] |
- | [[Category: Fellert | + | [[Category: Backmark A]] |
- | [[Category: Horsefield | + | [[Category: Fellert M]] |
- | [[Category: Johanson | + | [[Category: Horsefield R]] |
- | [[Category: Kjellbom | + | [[Category: Johanson U]] |
- | [[Category: Kvassman | + | [[Category: Kjellbom P]] |
- | [[Category: Neutze | + | [[Category: Kvassman J]] |
- | [[Category: Norden | + | [[Category: Neutze R]] |
- | [[Category: | + | [[Category: Norden K]] |
- | [[Category: Tornroth-Horsefield | + | [[Category: Terwisscha Van Scheltinga AC]] |
- | + | [[Category: Tornroth-Horsefield S]] | |
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Current revision
Human Aquaporin 5 (AQP5) - High Resolution X-ray Structure
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