1fnz

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[[Image:1fnz.gif|left|200px]]
 
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{{Structure
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==A bark lectin from robinia pseudoacacia in complex with N-acetylgalactosamine==
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|PDB= 1fnz |SIZE=350|CAPTION= <scene name='initialview01'>1fnz</scene>, resolution 2.05&Aring;
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<StructureSection load='1fnz' size='340' side='right'caption='[[1fnz]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:A2g+Binding+Site+For+Residue+A+555'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+A+500'>AC2</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
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<table><tr><td colspan='2'>[[1fnz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Robinia_pseudoacacia Robinia pseudoacacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FNZ FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fnz OCA], [https://pdbe.org/1fnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fnz RCSB], [https://www.ebi.ac.uk/pdbsum/1fnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fnz ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1fny|1FNY]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fnz OCA], [http://www.ebi.ac.uk/pdbsum/1fnz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1fnz RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/LCB1_ROBPS LCB1_ROBPS]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/1fnz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fnz ConSurf].
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<div style="clear:both"></div>
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'''A bark lectin from robinia pseudoacacia in complex with N-acetylgalactosamine'''
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==See Also==
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*[[Agglutinin 3D structures|Agglutinin 3D structures]]
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__TOC__
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==Overview==
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</StructureSection>
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The structure of the bark lectin RPbAI (isoform A4) from Robinia pseudoacacia has been determined by protein crystallography both in the free form and complexed with N-acetylgalactosamine. The free form is refined at 1.80 A resolution to an R-factor of 18.9% whereas the complexed structure has an R-factor of 19.7% at 2.05 A resolution. Both structures are compared to each other and to other available legume lectin structures. The polypeptide chains of the two structures exhibit the characteristic legume lectin tertiary fold. The quaternary structure resembles that of the Phaseolus vulgaris lectin, the soybean agglutinin, and the Dolichos biflorus lectin, but displays some unique features leading to the extreme stability of this lectin.
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[[Category: Large Structures]]
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==About this Structure==
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1FNZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Robinia_pseudoacacia Robinia pseudoacacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNZ OCA].
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==Reference==
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Structure of a legume lectin from the bark of Robinia pseudoacacia and its complex with N-acetylgalactosamine., Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Proteins. 2001 Sep 1;44(4):470-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11484224 11484224]
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[[Category: Robinia pseudoacacia]]
[[Category: Robinia pseudoacacia]]
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[[Category: Single protein]]
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[[Category: Barre A]]
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[[Category: Barre, A.]]
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[[Category: De Ranter CJ]]
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[[Category: Damme, E J.Van.]]
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[[Category: Peumans WJ]]
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[[Category: Peumans, W J.]]
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[[Category: Rabijns A]]
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[[Category: Rabijns, A.]]
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[[Category: Rouge P]]
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[[Category: Ranter, C J.De.]]
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[[Category: Van Damme EJ]]
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[[Category: Rouge, P.]]
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[[Category: Verboven C]]
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[[Category: Verboven, C.]]
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[[Category: jelly roll]]
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[[Category: sugar binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:26:43 2008''
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Current revision

A bark lectin from robinia pseudoacacia in complex with N-acetylgalactosamine

PDB ID 1fnz

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