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2pbf

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==Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine==
==Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine==
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<StructureSection load='2pbf' size='340' side='right' caption='[[2pbf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2pbf' size='340' side='right'caption='[[2pbf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2pbf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PBF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2pbf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PBF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF14_0309 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-L-isoaspartate(D-aspartate)_O-methyltransferase Protein-L-isoaspartate(D-aspartate) O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.77 2.1.1.77] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbf OCA], [https://pdbe.org/2pbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pbf RCSB], [https://www.ebi.ac.uk/pdbsum/2pbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pbf ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbf OCA], [http://pdbe.org/2pbf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pbf RCSB], [http://www.ebi.ac.uk/pdbsum/2pbf PDBsum]</span></td></tr>
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</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pbf_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pbf_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Plaf7]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Bochkarev, A]]
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[[Category: Arrowsmith CH]]
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[[Category: Edwards, A M]]
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[[Category: Bochkarev A]]
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[[Category: Hassanali, A]]
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[[Category: Edwards AM]]
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[[Category: Hui, R]]
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[[Category: Hassanali A]]
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[[Category: Kozieradzki, I]]
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[[Category: Hui R]]
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[[Category: Lew, J]]
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[[Category: Kozieradzki I]]
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[[Category: Lin, L]]
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[[Category: Lew J]]
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[[Category: Qiu, W]]
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[[Category: Lin L]]
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[[Category: Ravichandran, M]]
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[[Category: Qiu W]]
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[[Category: Structural genomic]]
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[[Category: Ravichandran M]]
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[[Category: Sundstrom, M]]
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[[Category: Sundstrom M]]
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[[Category: Vedadi, M]]
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[[Category: Vedadi M]]
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[[Category: Wasney, G]]
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[[Category: Wasney G]]
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[[Category: Weigelt, J]]
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[[Category: Weigelt J]]
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[[Category: Wernimont, A K]]
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[[Category: Wernimont AK]]
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[[Category: Zhao, Y]]
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[[Category: Zhao Y]]
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[[Category: Isoaspartyl formation]]
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[[Category: Methyltransferase]]
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[[Category: P. falciparum]]
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[[Category: Protein repair]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine

PDB ID 2pbf

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