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2ond

From Proteopedia

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==Crystal Structure of the HAT-C domain of murine CstF-77==
==Crystal Structure of the HAT-C domain of murine CstF-77==
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<StructureSection load='2ond' size='340' side='right' caption='[[2ond]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='2ond' size='340' side='right'caption='[[2ond]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ond]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OND OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OND FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ond]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OND OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OND FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cstf3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ond FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ond OCA], [http://pdbe.org/2ond PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ond RCSB], [http://www.ebi.ac.uk/pdbsum/2ond PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ond FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ond OCA], [https://pdbe.org/2ond PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ond RCSB], [https://www.ebi.ac.uk/pdbsum/2ond PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ond ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CSTF3_MOUSE CSTF3_MOUSE]] One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity).
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[https://www.uniprot.org/uniprot/CSTF3_MOUSE CSTF3_MOUSE] One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2ond_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2ond_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Auperin, T C]]
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[[Category: Mus musculus]]
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[[Category: Bai, Y]]
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[[Category: Auperin TC]]
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[[Category: Chang, G G]]
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[[Category: Bai Y]]
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[[Category: Chou, C Y]]
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[[Category: Chang G-G]]
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[[Category: Manley, J L]]
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[[Category: Chou C-Y]]
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[[Category: Tong, L]]
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[[Category: Manley JL]]
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[[Category: Hat domain]]
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[[Category: Tong L]]
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[[Category: Structural protein]]
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Current revision

Crystal Structure of the HAT-C domain of murine CstF-77

PDB ID 2ond

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