3a7p

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==The crystal structure of Saccharomyces cerevisiae Atg16==
==The crystal structure of Saccharomyces cerevisiae Atg16==
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<StructureSection load='3a7p' size='340' side='right' caption='[[3a7p]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='3a7p' size='340' side='right'caption='[[3a7p]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3a7p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A7P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A7P FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3a7p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A7P FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3a7o|3a7o]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATG16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a7p OCA], [https://pdbe.org/3a7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a7p RCSB], [https://www.ebi.ac.uk/pdbsum/3a7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a7p ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a7p OCA], [http://pdbe.org/3a7p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a7p RCSB], [http://www.ebi.ac.uk/pdbsum/3a7p PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ATG16_YEAST ATG16_YEAST]] Stabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. Required for ATG8 localization to the pre-autophagosomal structure.<ref>PMID:8224160</ref> <ref>PMID:8663607</ref> <ref>PMID:10406794</ref> <ref>PMID:11689437</ref> <ref>PMID:11897782</ref>
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[https://www.uniprot.org/uniprot/ATG16_YEAST ATG16_YEAST] Stabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. Required for ATG8 localization to the pre-autophagosomal structure.<ref>PMID:8224160</ref> <ref>PMID:8663607</ref> <ref>PMID:10406794</ref> <ref>PMID:11689437</ref> <ref>PMID:11897782</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a7/3a7p_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a7/3a7p_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Autophagy-related protein|Autophagy-related protein]]
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*[[Autophagy-related protein 3D structures|Autophagy-related protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
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[[Category: Large Structures]]
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[[Category: Fujioka, Y]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Inagaki, F]]
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[[Category: Fujioka Y]]
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[[Category: Noda, N N]]
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[[Category: Inagaki F]]
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[[Category: Autophagy]]
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[[Category: Noda NN]]
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[[Category: Coiled-coil]]
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[[Category: Cytoplasmic vesicle]]
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[[Category: Protein transport]]
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[[Category: Transport]]
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[[Category: Vacuole]]
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Current revision

The crystal structure of Saccharomyces cerevisiae Atg16

PDB ID 3a7p

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