4x22

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==Crystal structure of Leptospira Interrogans Triosephosphate Isomerase (LiTIM)==
==Crystal structure of Leptospira Interrogans Triosephosphate Isomerase (LiTIM)==
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<StructureSection load='4x22' size='340' side='right' caption='[[4x22]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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<StructureSection load='4x22' size='340' side='right'caption='[[4x22]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4x22]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X22 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4x22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptospira_interrogans_serovar_Icterohaemorrhagiae_str._RGA Leptospira interrogans serovar Icterohaemorrhagiae str. RGA]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X22 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.084&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x22 OCA], [http://pdbe.org/4x22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x22 RCSB], [http://www.ebi.ac.uk/pdbsum/4x22 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x22 OCA], [https://pdbe.org/4x22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x22 RCSB], [https://www.ebi.ac.uk/pdbsum/4x22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x22 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPIS_LEPIN TPIS_LEPIN] Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).[HAMAP-Rule:MF_00147]
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==See Also==
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*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Triose-phosphate isomerase]]
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[[Category: Large Structures]]
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[[Category: Balaram, P]]
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[[Category: Leptospira interrogans serovar Icterohaemorrhagiae str. RGA]]
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[[Category: Murthy, M R.N]]
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[[Category: Balaram P]]
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[[Category: Pareek, V]]
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[[Category: Murthy MRN]]
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[[Category: Beta-alpha barrel]]
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[[Category: Pareek V]]
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[[Category: Isomerase]]
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[[Category: Tim barrel]]
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Current revision

Crystal structure of Leptospira Interrogans Triosephosphate Isomerase (LiTIM)

PDB ID 4x22

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