1fz6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:20, 7 February 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1fz6.gif|left|200px]]
 
-
{{Structure
+
==METHANE MONOOXYGENASE HYDROXYLASE, FORM II SOAKED IN 1 M METHANOL==
-
|PDB= 1fz6 |SIZE=350|CAPTION= <scene name='initialview01'>1fz6</scene>, resolution 2.05&Aring;
+
<StructureSection load='1fz6' size='340' side='right'caption='[[1fz6]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>
+
<table><tr><td colspan='2'>[[1fz6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FZ6 FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methane_monooxygenase Methane monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.25 1.14.13.25] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fz6 OCA], [https://pdbe.org/1fz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fz6 RCSB], [https://www.ebi.ac.uk/pdbsum/1fz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fz6 ProSAT]</span></td></tr>
-
|RELATEDENTRY=
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fz6 OCA], [http://www.ebi.ac.uk/pdbsum/1fz6 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1fz6 RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/MEMG_METCA MEMG_METCA] Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fz/1fz6_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fz6 ConSurf].
 +
<div style="clear:both"></div>
-
'''METHANE MONOOXYGENASE HYDROXYLASE, FORM II SOAKED IN 1 M METHANOL'''
+
==See Also==
-
 
+
*[[Methane monooxygenase 3D structures|Methane monooxygenase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
1FZ6 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZ6 OCA].
+
[[Category: Large Structures]]
-
 
+
-
==Reference==
+
-
X-ray crystal structure of alcohol products bound at the active site of soluble methane monooxygenase hydroxylase., Whittington DA, Sazinsky MH, Lippard SJ, J Am Chem Soc. 2001 Feb 28;123(8):1794-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11456795 11456795]
+
-
[[Category: Methane monooxygenase]]
+
[[Category: Methylococcus capsulatus]]
[[Category: Methylococcus capsulatus]]
-
[[Category: Protein complex]]
+
[[Category: Lippard SJ]]
-
[[Category: Lippard, S J.]]
+
[[Category: Sazinsky MH]]
-
[[Category: Sazinsky, M H.]]
+
[[Category: Whittington DA]]
-
[[Category: Whittington, D A.]]
+
-
[[Category: dinuclear iron center]]
+
-
[[Category: monooxygenase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:33:07 2008''
+

Current revision

METHANE MONOOXYGENASE HYDROXYLASE, FORM II SOAKED IN 1 M METHANOL

PDB ID 1fz6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1fz6"
Personal tools