This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2mza
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Phosphorylation of CB1 Cannabinoid Receptor Fourth Intracellular Loop pepducins: Effects on Structure and Function== | ==Phosphorylation of CB1 Cannabinoid Receptor Fourth Intracellular Loop pepducins: Effects on Structure and Function== | ||
| - | <StructureSection load='2mza' size='340' side='right' caption='[[2mza | + | <StructureSection load='2mza' size='340' side='right'caption='[[2mza]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2mza]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MZA OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[2mza]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MZA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mza OCA], [https://pdbe.org/2mza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mza RCSB], [https://www.ebi.ac.uk/pdbsum/2mza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mza ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CNR1_HUMAN CNR1_HUMAN] Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.<ref>PMID:15620723</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Chandrashekaran I]] |
| - | [[Category: | + | [[Category: Cowsik S]] |
| - | [[Category: | + | [[Category: Eldeeb K]] |
| - | [[Category: | + | [[Category: Ganjiwale A]] |
| - | [[Category: | + | [[Category: Howlett A]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Phosphorylation of CB1 Cannabinoid Receptor Fourth Intracellular Loop pepducins: Effects on Structure and Function
| |||||||||||
