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A-RNA tour
From Proteopedia
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==A-form RNA== | ==A-form RNA== | ||
| - | <StructureSection load='1rna' size=' | + | <StructureSection load='1rna' size='350' side='right' caption='A-RNA [[1rna]]' scene='72/725869/A-rna_overview/1'> |
| + | Source <ref>PMID:7071593</ref> | ||
== Structural highlights == | == Structural highlights == | ||
<UL> | <UL> | ||
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You can <scene name='72/725869/Zoom_pairs/1'>look at just four of the base pairs.</scene>.You are looking into the major groove and the colors of the base pairs alternate. You can also <scene name='72/725869/Zoom_pairs_only/1'>look at just the bases</scene>. | You can <scene name='72/725869/Zoom_pairs/1'>look at just four of the base pairs.</scene>.You are looking into the major groove and the colors of the base pairs alternate. You can also <scene name='72/725869/Zoom_pairs_only/1'>look at just the bases</scene>. | ||
Each base pair stacks on the next similarly, as shown from <scene name='72/725869/Zoom_pairs_top/1'>this top view</scene>. This is the <scene name='72/725869/Zoom_pairs_only_top/1'>same top view of just the bases</scene>. | Each base pair stacks on the next similarly, as shown from <scene name='72/725869/Zoom_pairs_top/1'>this top view</scene>. This is the <scene name='72/725869/Zoom_pairs_only_top/1'>same top view of just the bases</scene>. | ||
| - | B-DNA stacks similarly, but compare this with Z-DNA, which behaves much differently. Essentially all helical RNA is in A form, but DNA can also be found in A form under certain conditions (particularly in RNA-DNA hybrids). The 2'-OH of ribose favors the C3'-''endo'' sugar pucker necessary for A-form geometry. | + | B-DNA stacks similarly, but compare this with Z-DNA, which behaves much differently. Essentially all helical RNA is in A form, but DNA can also be found in A form under certain conditions (particularly in RNA-DNA hybrids). The 2'-OH of ribose favors the C3'-''endo'' sugar pucker necessary for A-form geometry. The O2' is easily seen as white spheres in <scene name='72/725869/Rna_space_filling_o2prime/1'>this space fill view</scene>. |
| - | You can compare it with the DNA forms by looking at this [ | + | You can compare it with the DNA forms by looking at this [[Media:JnABZ3d.gif|3D red-blue stereo picture of A, B, and Z DNA]] |
</StructureSection> | </StructureSection> | ||
| + | ==See Also== | ||
| + | * [[Z-DNA model tour]] and [[Z-DNA]] | ||
| + | * [[B-DNA tour]] | ||
| + | *[[Transfer RNA tour]] | ||
| + | * A more general overview will be found at [[DNA]]. | ||
| + | * [[Forms of DNA]] shows a side-by-side comparison of A, B, and Z forms of DNA. | ||
| + | * An interactive tutorial on [http://dna.molviz.org DNA Structure], ''disponible también en español'' and eight other languages. | ||
== References == | == References == | ||
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JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
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| + | <references /> | ||
Current revision
A-form RNA
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See Also
- Z-DNA model tour and Z-DNA
- B-DNA tour
- Transfer RNA tour
- A more general overview will be found at DNA.
- Forms of DNA shows a side-by-side comparison of A, B, and Z forms of DNA.
- An interactive tutorial on DNA Structure, disponible también en español and eight other languages.
References
JSmol in Proteopedia [2] or to the article describing Jmol [3] to the rescue.
- ↑ Dickerson RE, Drew HR, Conner BN, Wing RM, Fratini AV, Kopka ML. The anatomy of A-, B-, and Z-DNA. Science. 1982 Apr 30;216(4545):475-85. PMID:7071593
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
