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4q7g

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==1.7 Angstrom Crystal Structure of leukotoxin LukD from Staphylococcus aureus.==
==1.7 Angstrom Crystal Structure of leukotoxin LukD from Staphylococcus aureus.==
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<StructureSection load='4q7g' size='340' side='right' caption='[[4q7g]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4q7g' size='340' side='right'caption='[[4q7g]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4q7g]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q7G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4q7g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MSSA476 Staphylococcus aureus subsp. aureus MSSA476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q7G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q7g OCA], [http://pdbe.org/4q7g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q7g RCSB], [http://www.ebi.ac.uk/pdbsum/4q7g PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q7g OCA], [https://pdbe.org/4q7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q7g RCSB], [https://www.ebi.ac.uk/pdbsum/4q7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q7g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LUKDV_STAAS LUKDV_STAAS]] Part of a bi-component leucotoxin that acts by forming pores in the membrane of the target cells. The activity of LukEv-LukDv to rabbit leukocytes is similar to that of the Panton-Valentine leucocidin (PVL). LukEv-LukDv is hemolytic to rabbit red blood cells although the activity is only 8% of gamma-hemolysin (By similarity).
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[https://www.uniprot.org/uniprot/A0A0H2WX25_STAAC A0A0H2WX25_STAAC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anderson, W F]]
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[[Category: Large Structures]]
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[[Category: Bagnoli, F]]
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[[Category: Staphylococcus aureus subsp. aureus MSSA476]]
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[[Category: Bottomley, M]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Bagnoli F]]
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[[Category: Falugi, F]]
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[[Category: Bottomley M]]
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[[Category: Grandi, G]]
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[[Category: Falugi F]]
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[[Category: Kwon, K]]
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[[Category: Grandi G]]
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[[Category: Minasov, G]]
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[[Category: Kwon K]]
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[[Category: Nocadello, S]]
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[[Category: Minasov G]]
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[[Category: Shatsman, S]]
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[[Category: Nocadello S]]
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[[Category: Shuvalova, L]]
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[[Category: Shatsman S]]
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[[Category: Csgid]]
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[[Category: Shuvalova L]]
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[[Category: Distorted sandwich]]
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[[Category: Leukocidin]]
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[[Category: Leukocidin-like]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Toxin]]
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Current revision

1.7 Angstrom Crystal Structure of leukotoxin LukD from Staphylococcus aureus.

PDB ID 4q7g

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