Follicle-stimulating hormone
From Proteopedia
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- | <StructureSection load=' | + | <StructureSection load='' size='350' side='right' caption='Human glycosylated FSH α chain (cyan, pink), β chain (green, yellow) complex with sulfate (PDB entry [[1fl7]])' scene='54/540141/Cv/1'> |
+ | == Function == | ||
'''Follicle-stimulating hormone''' (FSH) is secreted by the anterior pituitary gland. FSH regulates development, growth and pubertal maturation of the human body<ref>PMID:6267989</ref>. | '''Follicle-stimulating hormone''' (FSH) is secreted by the anterior pituitary gland. FSH regulates development, growth and pubertal maturation of the human body<ref>PMID:6267989</ref>. | ||
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For details see<br /> | For details see<br /> | ||
[[Human Follicle-Stimulating Hormone Complexed with its Receptor]]<br /> | [[Human Follicle-Stimulating Hormone Complexed with its Receptor]]<br /> | ||
- | [[Leucine-rich repeat]] | + | [[Leucine-rich repeat]]<br /> |
- | + | [[FSH (Hebrew)]]. | |
See also [[Hormone]]. | See also [[Hormone]]. | ||
+ | |||
+ | ==Relevance== | ||
+ | |||
+ | FSH level is measured by a blood test in order to evaluate various infertility and menopause problems. | ||
==3D structures of follicle-stimulating hormone== | ==3D structures of follicle-stimulating hormone== | ||
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[[1fl7]] – hFSH – human<br /> | [[1fl7]] – hFSH – human<br /> | ||
[[1xwd]] – hFSH + a significant portion of the FSH receptor extracellular domain<br /> | [[1xwd]] – hFSH + a significant portion of the FSH receptor extracellular domain<br /> | ||
- | [[4ay9]] – hFSH + the entire FSH receptor extracellular domain | + | [[4ay9]] – hFSH + the entire FSH receptor extracellular domain<br /> |
+ | [[4mqw]] – hFSH β + FSH receptor + glycoprotein hormone<br /> | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
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