5i3o

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Current revision (08:22, 23 August 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5i3o is ON HOLD until Mar 09 2017
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==Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor==
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<StructureSection load='5i3o' size='340' side='right'caption='[[5i3o]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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Authors: Counago, R.M., Sorrell, F.J., Krojer, T., Elkins, J.M., Gileadi, O., Willson, T.M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Arruda, P., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5i3o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I3O FirstGlance]. <br>
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Description: Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IDV:N-(6-{3-[(DIMETHYLSULFAMOYL)AMINO]PHENYL}-1H-INDAZOL-3-YL)CYCLOPROPANECARBOXAMIDE'>IDV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Elkins, J.M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i3o OCA], [https://pdbe.org/5i3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i3o RCSB], [https://www.ebi.ac.uk/pdbsum/5i3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i3o ProSAT]</span></td></tr>
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[[Category: Counago, R.M]]
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</table>
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[[Category: Krojer, T]]
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== Function ==
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[[Category: Bountra, C]]
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[https://www.uniprot.org/uniprot/BMP2K_HUMAN BMP2K_HUMAN] May be involved in osteoblast differentiation.
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[[Category: Sorrell, F.J]]
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__TOC__
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[[Category: Arrowsmith, C.H]]
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</StructureSection>
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[[Category: Edwards, A.M]]
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[[Category: Homo sapiens]]
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[[Category: Willson, T.M]]
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[[Category: Large Structures]]
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[[Category: Gileadi, O]]
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[[Category: Arrowsmith CH]]
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[[Category: Arruda, P]]
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[[Category: Arruda P]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Axtman A]]
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[[Category: Bountra C]]
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[[Category: Counago RM]]
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[[Category: Drewry D]]
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[[Category: Edwards AM]]
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[[Category: Elkins JM]]
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[[Category: Gileadi O]]
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[[Category: Krojer T]]
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[[Category: Savitsky P]]
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[[Category: Sorrell FJ]]
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[[Category: Wells C]]
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[[Category: Willson TM]]
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[[Category: Zhang C]]
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[[Category: Zuercher W]]

Current revision

Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor

PDB ID 5i3o

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OCA

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