5ahi

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==Crystal structure of salmonalla enterica HisA mutant D7N with ProFAR==
==Crystal structure of salmonalla enterica HisA mutant D7N with ProFAR==
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<StructureSection load='5ahi' size='340' side='right' caption='[[5ahi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='5ahi' size='340' side='right'caption='[[5ahi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ahi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AHI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AHI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ahi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AHI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GUO:[(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[(E)-[[(2R,3R,4S,5R)-3,4-BIS(OXIDANYL)-5-(PHOSPHONOOXYMETHYL)OXOLAN-2-YL]AMINO]METHYLIDENEAMINO]IMIDAZOL-1-YL]-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>GUO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.999&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ahe|5ahe]], [[5ahf|5ahf]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GUO:[(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[(E)-[[(2R,3R,4S,5R)-3,4-BIS(OXIDANYL)-5-(PHOSPHONOOXYMETHYL)OXOLAN-2-YL]AMINO]METHYLIDENEAMINO]IMIDAZOL-1-YL]-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>GUO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-(5-phosphoribosyl)-5-_((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide_isomerase 1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.16 5.3.1.16] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ahi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ahi OCA], [https://pdbe.org/5ahi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ahi RCSB], [https://www.ebi.ac.uk/pdbsum/5ahi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ahi ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ahi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ahi OCA], [http://pdbe.org/5ahi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ahi RCSB], [http://www.ebi.ac.uk/pdbsum/5ahi PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HIS4_SALTY HIS4_SALTY]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Evans, G B]]
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[[Category: Large Structures]]
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[[Category: Guo, X]]
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[[Category: Salmonella enterica]]
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[[Category: Nasvall, J]]
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[[Category: Evans GB]]
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[[Category: Newton, M S]]
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[[Category: Guo X]]
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[[Category: Patrick, W M]]
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[[Category: Nasvall J]]
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[[Category: Selmer, M]]
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[[Category: Newton MS]]
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[[Category: Soderholm, A]]
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[[Category: Patrick WM]]
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[[Category: Hisa]]
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[[Category: Selmer M]]
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[[Category: Histidine biosynthesis]]
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[[Category: Soderholm A]]
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[[Category: Isomerase]]
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Current revision

Crystal structure of salmonalla enterica HisA mutant D7N with ProFAR

PDB ID 5ahi

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