User:Allie Paton/Sandbox 1181
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==Structure of Class B Human Glucagon G-Protein Coupled Receptors== | ==Structure of Class B Human Glucagon G-Protein Coupled Receptors== | ||
- | <StructureSection load='4L6R' size='340' side='right' caption='7TM Helical Structure of 4L6R GPCR' scene=' | + | <StructureSection load='4L6R' size='340' side='right' caption='7TM Helical Structure of 4L6R GPCR' scene='72/727084/Scene_1/2'> |
This is a default text for your page '''Allie Paton/Sandbox 1181'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Allie Paton/Sandbox 1181'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
- | == | + | <scene name='72/727084/Scene_1/2'>Nucleotide 200-205</scene> |
- | == | + | <scene name='72/727084/Temp_map/1'>Temp Map</scene> |
- | + | ||
+ | == Function of Glucagon Receptor == | ||
+ | |||
== Disease == | == Disease == | ||
+ | === Diabetes Mellitus === | ||
+ | === Biological Function of Glucagon === | ||
- | == | + | == Biochemical Significance == |
- | === | + | === Kinetics === |
+ | === Ligand Binding === | ||
+ | === Sequence Conservation and Homology === | ||
+ | === Conformational Change === | ||
== Structural highlights == | == Structural highlights == | ||
- | === | + | === Crucial Structural Interactions === |
+ | === Peptide Sequence === | ||
+ | === Active Binding Sites === | ||
+ | |||
+ | |||
+ | == Relevance == | ||
+ | === Class B in Comparison to Class A === | ||
+ | [[Image:Class B.png |100 px|left|thumb|Figure Legend]] | ||
+ | ==== Structural Similarities ==== | ||
+ | ==== Sequential Similarities ==== | ||
+ | === Current Drug Targets === | ||
+ | |||
+ | == Future Direction == | ||
+ | === Drug Development === | ||
+ | === Possible Structures for Agonists === | ||
+ | |||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. |
Current revision
Structure of Class B Human Glucagon G-Protein Coupled Receptors
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644