5fwc
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==Human Spectrin SH3 domain D48G, E7A, K60A== |
| + | <StructureSection load='5fwc' size='340' side='right'caption='[[5fwc]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5fwc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FWC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwc OCA], [https://pdbe.org/5fwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fwc RCSB], [https://www.ebi.ac.uk/pdbsum/5fwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. | ||
| - | + | ==See Also== | |
| - | + | *[[Spectrin 3D structures|Spectrin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Gallego | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Gallego P]] |
| - | [[Category: Ventura | + | [[Category: Navarro S]] |
| + | [[Category: Reverter D]] | ||
| + | [[Category: Ventura S]] | ||
Current revision
Human Spectrin SH3 domain D48G, E7A, K60A
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