5hcp
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of antimicrobial peptide Metalnikowin bound to the Thermus thermophilus 70S ribosome== | |
| + | <StructureSection load='5hcp' size='340' side='right'caption='[[5hcp]], [[Resolution|resolution]] 2.89Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5hcp]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HCP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.894Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hcp OCA], [https://pdbe.org/5hcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hcp RCSB], [https://www.ebi.ac.uk/pdbsum/5hcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hcp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RL2_THET8 RL2_THET8] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial (By similarity). Makes several contacts with the 16S rRNA (forming bridge B7b) in the 70S ribosome.[HAMAP-Rule:MF_01320_B] | ||
| - | + | ==See Also== | |
| - | + | *[[Ribosomal protein THX 3D structures|Ribosomal protein THX 3D structures]] | |
| - | + | *[[Ribosome 3D structures|Ribosome 3D structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Florin | + | [[Category: Large Structures]] |
| - | [[Category: Gagnon | + | [[Category: Thermus thermophilus HB8]] |
| - | [[Category: | + | [[Category: Florin T]] |
| - | [[Category: Mankin | + | [[Category: Gagnon MG]] |
| - | [[Category: | + | [[Category: Lomakin IB]] |
| + | [[Category: Mankin AS]] | ||
| + | [[Category: Roy RN]] | ||
| + | [[Category: Steitz TA]] | ||
Current revision
Crystal structure of antimicrobial peptide Metalnikowin bound to the Thermus thermophilus 70S ribosome
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