5hcq
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of antimicrobial peptide Oncocin d15-19 bound to the Thermus thermophilus 70S ribosome== | |
| + | <StructureSection load='5hcq' size='340' side='right'caption='[[5hcq]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5hcq]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HCQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HCQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.801Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hcq OCA], [https://pdbe.org/5hcq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hcq RCSB], [https://www.ebi.ac.uk/pdbsum/5hcq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hcq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RL2_THET8 RL2_THET8] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial (By similarity). Makes several contacts with the 16S rRNA (forming bridge B7b) in the 70S ribosome.[HAMAP-Rule:MF_01320_B] | ||
| - | + | ==See Also== | |
| - | + | *[[Ribosomal protein THX 3D structures|Ribosomal protein THX 3D structures]] | |
| - | + | *[[Ribosome 3D structures|Ribosome 3D structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Florin | + | [[Category: Large Structures]] |
| - | [[Category: Gagnon | + | [[Category: Thermus thermophilus HB8]] |
| - | [[Category: | + | [[Category: Florin T]] |
| - | [[Category: Mankin | + | [[Category: Gagnon MG]] |
| - | [[Category: | + | [[Category: Lomakin IB]] |
| + | [[Category: Mankin AS]] | ||
| + | [[Category: Roy RN]] | ||
| + | [[Category: Steitz TA]] | ||
Current revision
Crystal structure of antimicrobial peptide Oncocin d15-19 bound to the Thermus thermophilus 70S ribosome
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