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5il8
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5il8 is ON HOLD Authors: Koo, H.J., Louie, G.V., Xu, Y., Bowman, M., Noel, J.P. Description: Tobacco 5-epi-aristolochene synthase with MOPSO buffer...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Tobacco 5-epi-aristolochene synthase with MOPSO buffer molecule and Ca2+ ions== | |
| - | + | <StructureSection load='5il8' size='340' side='right'caption='[[5il8]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5il8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IL8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6BX:(2S)-2-HYDROXY-3-(MORPHOLIN-4-YL)PROPANE-1-SULFONIC+ACID'>6BX</scene>, <scene name='pdbligand=6BY:(2R)-2-HYDROXY-3-(MORPHOLIN-4-YL)PROPANE-1-SULFONIC+ACID'>6BY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5il8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5il8 OCA], [https://pdbe.org/5il8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5il8 RCSB], [https://www.ebi.ac.uk/pdbsum/5il8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5il8 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene. |
| - | [[Category: Noel | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Nicotiana tabacum]] | ||
| + | [[Category: Bowman M]] | ||
| + | [[Category: Koo HJ]] | ||
| + | [[Category: Louie GV]] | ||
| + | [[Category: Noel JP]] | ||
| + | [[Category: Xu Y]] | ||
Current revision
Tobacco 5-epi-aristolochene synthase with MOPSO buffer molecule and Ca2+ ions
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Categories: Large Structures | Nicotiana tabacum | Bowman M | Koo HJ | Louie GV | Noel JP | Xu Y
