Insulin-like growth factor binding protein

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*IGFBP-1 is closely related to risk factors for diabetes and cardiovascular disease<ref>PMID:11317665</ref>.
*IGFBP-1 is closely related to risk factors for diabetes and cardiovascular disease<ref>PMID:11317665</ref>.
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</StructureSection>
 
==3D structures of insulin-like growth factor binding protein==
==3D structures of insulin-like growth factor binding protein==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[Insulin-like growth factor binding protein 3D structures]]
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*IGF binding protein 1
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**[[1zt3]], [[1zt5]] – hIGFBP C terminal + IGF I – human <br />
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</StructureSection>
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**[[2dsq]] – hIGFBP C terminal + hIGFBP-4 N terminal + IGF I <br />
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*IGF binding protein 2
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**[[2h7t]] – hIGFBP C terminal – NMR<br />
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*IGF binding protein 4
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**[[1wqj]], [[2dsp]] – hIGFBP binding domain + IGF I <br />
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**[[2dsr]] – hIGFBP N terminal + C terminal + IGF I <br />
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*IGF binding protein 5
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**[[1boe]] – hIGFBP binding domain + IGF I – NMR<br />
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**[[1h59]] – hIGFBP binding domain + IGF I <br />
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*IGF binding protein 6
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**[[1rmj]] – hIGFBP C terminal – NMR<br />
 
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**[[2jm2]] – hIGFBP N terminal – NMR<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
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[[Category:Topic Page]]

Current revision

Insulin-like growth factor binding protein N terminal (green) complex with Insulin-like growth factor I (wheat) (PDB code 2dsp)

Drag the structure with the mouse to rotate

References

  1. ↑ Hwa V, Oh Y, Rosenfeld RG. The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr Rev. 1999 Dec;20(6):761-87. PMID:10605625 doi:http://dx.doi.org/10.1210/edrv.20.6.0382
  2. ↑ Bach LA, Fu P, Yang Z. Insulin-like growth factor-binding protein-6 and cancer. Clin Sci (Lond). 2013 Feb;124(4):215-29. doi: 10.1042/CS20120343. PMID:23126425 doi:http://dx.doi.org/10.1042/CS20120343
  3. ↑ Rocha RL, Hilsenbeck SG, Jackson JG, VanDenBerg CL, Weng Cn, Lee AV, Yee D. Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival. Clin Cancer Res. 1997 Jan;3(1):103-9. PMID:9815544
  4. ↑ Kirman I, Whelan RL, Jain S, Nielsen SE, Seidelin JB, Nielsen OH. Insulin-like growth factor binding protein 3 in inflammatory bowel disease. Dig Dis Sci. 2005 Apr;50(4):780-4. PMID:15844718
  5. ↑ Durai R, Davies M, Yang W, Yang SY, Seifalian A, Goldspink G, Winslet M. Biology of insulin-like growth factor binding protein-4 and its role in cancer (review). Int J Oncol. 2006 Jun;28(6):1317-25. PMID:16685432
  6. ↑ Heald AH, Cruickshank JK, Riste LK, Cade JE, Anderson S, Greenhalgh A, Sampayo J, Taylor W, Fraser W, White A, Gibson JM. Close relation of fasting insulin-like growth factor binding protein-1 (IGFBP-1) with glucose tolerance and cardiovascular risk in two populations. Diabetologia. 2001 Mar;44(3):333-9. PMID:11317665 doi:http://dx.doi.org/10.1007/s001250051623

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