This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Met repressor
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 7: | Line 7: | ||
== Structural highlights == | == Structural highlights == | ||
| - | <scene name='53/536702/Cv/ | + | <scene name='53/536702/Cv/7'>EcMR (mutant) with corepressor SAM, Ca+2 ion and DNA</scene>. <scene name='53/536702/Cv/8'>SAM binds to MR in a hydrophobic pocket between 2 monomers</scene><ref>PMID:10986458</ref>. Water molecules are shown as red spheres. |
</StructureSection> | </StructureSection> | ||
== 3D Structures of Met repressor == | == 3D Structures of Met repressor == | ||
Current revision
| |||||||||||
3D Structures of Met repressor
Updated on 10-July-2019
1cmb – EcMR – Escherichia coli
1mjk – EcMR (mutant)
1cma – EcMR + DNA
1mjm – EcMR (mutant) + DNA
1cmc – EcMR + SAM
1mjl, 1mjp – EcMR (mutant) + SAM
1mj2, 1mjo, 1mjq – EcMR (mutant) + SAM + DNA
References
- ↑ Somers WS, Rafferty JB, Phillips K, Strathdee S, He YY, McNally T, Manfield I, Navratil O, Old IG, Saint-Girons I, et al.. The Met repressor-operator complex: DNA recognition by beta-strands. Ann N Y Acad Sci. 1994 Jul 29;726:105-17. PMID:8092669
- ↑ Garvie CW, Phillips SE. Direct and indirect readout in mutant Met repressor-operator complexes. Structure. 2000 Sep 15;8(9):905-14. PMID:10986458
