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5dkp
From Proteopedia
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==Crystal Structure of N. meningitidis ClpP in complex with agonist ADEP A54556.== | ==Crystal Structure of N. meningitidis ClpP in complex with agonist ADEP A54556.== | ||
| - | <StructureSection load='5dkp' size='340' side='right' caption='[[5dkp]], [[Resolution|resolution]] 2.38Å' scene=''> | + | <StructureSection load='5dkp' size='340' side='right'caption='[[5dkp]], [[Resolution|resolution]] 2.38Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5dkp]] is a 56 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DKP OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5dkp]] is a 56 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_MC58 Neisseria meningitidis MC58] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DKP FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.381Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MAA:N-METHYL-L-ALANINE'>MAA</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OTT:(2E,4E,6E)-OCTA-2,4,6-TRIENOIC+ACID'>OTT</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dkp OCA], [https://pdbe.org/5dkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dkp RCSB], [https://www.ebi.ac.uk/pdbsum/5dkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dkp ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CLPP_NEIMB CLPP_NEIMB] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.[HAMAP-Rule:MF_00444] |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5dkp" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5dkp" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Clp protease 3D structures|Clp protease 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Batey | + | [[Category: Neisseria meningitidis MC58]] |
| - | [[Category: Bryson | + | [[Category: Synthetic construct]] |
| - | [[Category: Eger | + | [[Category: Batey RA]] |
| - | [[Category: Goodreid | + | [[Category: Bryson S]] |
| - | [[Category: Gray-Owen | + | [[Category: Eger BT]] |
| - | [[Category: Houry | + | [[Category: Goodreid JD]] |
| - | [[Category: Janetzko | + | [[Category: Gray-Owen SD]] |
| - | [[Category: Leung | + | [[Category: Houry WA]] |
| - | [[Category: | + | [[Category: Janetzko J]] |
| - | [[Category: | + | [[Category: Leung E]] |
| - | [[Category: Walker | + | [[Category: Pai EF]] |
| - | [[Category: Wong | + | [[Category: Santa Maria Jr JP]] |
| - | + | [[Category: Walker S]] | |
| - | + | [[Category: Wong K]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of N. meningitidis ClpP in complex with agonist ADEP A54556.
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