1hky
From Proteopedia
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| - | + | ==Solution structure of a PAN module from Eimeria tenella== | |
| - | + | <StructureSection load='1hky' size='340' side='right'caption='[[1hky]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1hky]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eimeria_tenella Eimeria tenella]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HKY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hky OCA], [https://pdbe.org/1hky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hky RCSB], [https://www.ebi.ac.uk/pdbsum/1hky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hky ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/Q9U966_EIMTE Q9U966_EIMTE] | |
| - | + | <div style="background-color:#fffaf0;"> | |
| - | + | == Publication Abstract from PubMed == | |
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Micronemes, specialised organelles found in all apicomplexan parasites, secrete molecules that are essential for parasite attachment and invasion of host cells. EtMIC5 is one such microneme protein that contains eleven tandemly repeating modules. These modules have homology with the PAN module superfamily. Members of this family are found in blood clotting proteins, some growth factors and some nematode proteins. This paper presents the structure of the 9th PAN module in EtMIC5, determined using high resolution NMR. The structure shows similarities to and some differences from the N-terminal module of hepatocyte growth factor (HGF), the only previous member of the PAN family with known structure. | Micronemes, specialised organelles found in all apicomplexan parasites, secrete molecules that are essential for parasite attachment and invasion of host cells. EtMIC5 is one such microneme protein that contains eleven tandemly repeating modules. These modules have homology with the PAN module superfamily. Members of this family are found in blood clotting proteins, some growth factors and some nematode proteins. This paper presents the structure of the 9th PAN module in EtMIC5, determined using high resolution NMR. The structure shows similarities to and some differences from the N-terminal module of hepatocyte growth factor (HGF), the only previous member of the PAN family with known structure. | ||
| - | + | Solution structure of a PAN module from the apicomplexan parasite Eimeria tenella.,Brown PJ, Mulvey D, Potts JR, Tomley FM, Campbell ID J Struct Funct Genomics. 2003;4(4):227-34. PMID:15185963<ref>PMID:15185963</ref> | |
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| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 1hky" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Eimeria tenella]] | [[Category: Eimeria tenella]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Brown | + | [[Category: Brown PJ]] |
| - | [[Category: Campbell | + | [[Category: Campbell ID]] |
| - | [[Category: Mulvey | + | [[Category: Mulvey D]] |
| - | [[Category: Potts | + | [[Category: Potts JR]] |
| - | [[Category: Tomley | + | [[Category: Tomley FM]] |
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Current revision
Solution structure of a PAN module from Eimeria tenella
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