This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4cax

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:10, 9 May 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a pyrazole sulphonamide ligand (DDD85646)==
==Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a pyrazole sulphonamide ligand (DDD85646)==
-
<StructureSection load='4cax' size='340' side='right' caption='[[4cax]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
+
<StructureSection load='4cax' size='340' side='right'caption='[[4cax]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4cax]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CAX FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4cax]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus Aspergillus fumigatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CAX FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=646:2,6-DICHLORO-4-(2-PIPERAZIN-1-YLPYRIDIN-4-YL)-N-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)BENZENESULFONAMIDE'>646</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cav|4cav]], [[4caw|4caw]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=646:2,6-DICHLORO-4-(2-PIPERAZIN-1-YLPYRIDIN-4-YL)-N-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)BENZENESULFONAMIDE'>646</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cax OCA], [https://pdbe.org/4cax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cax RCSB], [https://www.ebi.ac.uk/pdbsum/4cax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cax ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cax OCA], [http://pdbe.org/4cax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cax RCSB], [http://www.ebi.ac.uk/pdbsum/4cax PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NMT_ASPFU NMT_ASPFU]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
+
[https://www.uniprot.org/uniprot/NMT_ASPFU NMT_ASPFU] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
+
[[Category: Aspergillus fumigatus]]
-
[[Category: Aalten, D M.F Van]]
+
[[Category: Large Structures]]
-
[[Category: Blair, D E]]
+
[[Category: Blair DE]]
-
[[Category: Fang, W]]
+
[[Category: Fang W]]
-
[[Category: Gilbert, I H]]
+
[[Category: Gilbert IH]]
-
[[Category: Harrison, J]]
+
[[Category: Harrison J]]
-
[[Category: Lockhart, D E.A]]
+
[[Category: Lockhart DEA]]
-
[[Category: Raimi, O G]]
+
[[Category: Raimi OG]]
-
[[Category: Robinson, D A]]
+
[[Category: Robinson DA]]
-
[[Category: Ruda, G F]]
+
[[Category: Ruda GF]]
-
[[Category: Torrie, L S]]
+
[[Category: Torrie LS]]
-
[[Category: Wyatt, P G]]
+
[[Category: Van Aalten DMF]]
-
[[Category: Drug discovery]]
+
[[Category: Wyatt PG]]
-
[[Category: Transferase]]
+

Current revision

Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a pyrazole sulphonamide ligand (DDD85646)

PDB ID 4cax

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4cax"
Personal tools