2nd1

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m (Protected "2nd1" [edit=sysop:move=sysop])
Current revision (07:04, 1 May 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 2nd1 is ON HOLD
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==Solution NMR structures of BRD4 ET domain in complex with NSD3_3 peptide==
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<StructureSection load='2nd1' size='340' side='right'caption='[[2nd1]]' scene=''>
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Authors: Zeng, L., Zhou, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2nd1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ND1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ND1 FirstGlance]. <br>
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Description: Solution NMR structures of BRD4 ET domain in complex with NSD3_3 peptide
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nd1 OCA], [https://pdbe.org/2nd1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nd1 RCSB], [https://www.ebi.ac.uk/pdbsum/2nd1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nd1 ProSAT]</span></td></tr>
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[[Category: Zhou, M]]
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</table>
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[[Category: Zeng, L]]
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== Disease ==
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[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Zeng L]]
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[[Category: Zhou M]]

Current revision

Solution NMR structures of BRD4 ET domain in complex with NSD3_3 peptide

PDB ID 2nd1

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