5dv2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human CNOT6L in complex with cytidine-5'-monophosphate== | |
| - | + | <StructureSection load='5dv2' size='340' side='right'caption='[[5dv2]], [[Resolution|resolution]] 2.07Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5dv2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DV2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene></td></tr> |
| - | [[Category: Bartlam | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dv2 OCA], [https://pdbe.org/5dv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dv2 RCSB], [https://www.ebi.ac.uk/pdbsum/5dv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dv2 ProSAT]</span></td></tr> |
| - | [[Category: Zhang | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CNO6L_HUMAN CNO6L_HUMAN] Plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA.<ref>PMID:17452450</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bartlam M]] | ||
| + | [[Category: Zhang Q]] | ||
Current revision
Crystal structure of human CNOT6L in complex with cytidine-5'-monophosphate
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