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5iuj
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5iuj is ON HOLD Authors: Trajtenberg, F., Imelio, J.A., Larrieux, N., Buschiazzo, A. Description: Crystal structure of the DesK-DesR complex in the...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM)== | |
| + | <StructureSection load='5iuj' size='340' side='right'caption='[[5iuj]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5iuj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IUJ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuj OCA], [https://pdbe.org/5iuj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iuj RCSB], [https://www.ebi.ac.uk/pdbsum/5iuj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DESK_BACSU DESK_BACSU] Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation.<ref>PMID:11285232</ref> <ref>PMID:11717295</ref> <ref>PMID:12207704</ref> <ref>PMID:14734164</ref> <ref>PMID:15090506</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Response regulator 3D structure|Response regulator 3D structure]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Imelio | + | </StructureSection> |
| - | [[Category: | + | [[Category: Bacillus subtilis subsp. subtilis str. 168]] |
| - | [[Category: Trajtenberg | + | [[Category: Large Structures]] |
| + | [[Category: Buschiazzo A]] | ||
| + | [[Category: Imelio JA]] | ||
| + | [[Category: Larrieux N]] | ||
| + | [[Category: Trajtenberg F]] | ||
Current revision
Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM)
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