5j50
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5j50 is ON HOLD until Paper Publication Authors: Abhinav, K.V., Sharma, K., Surolia, A., Vijayan, M. Description: Structure of tetrameric jacalin c...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of tetrameric jacalin complexed with Gal beta-(1,3) GalNAc-alpha-OPNP== | |
| + | <StructureSection load='5j50' size='340' side='right'caption='[[5j50]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5j50]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J50 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J50 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NPO:P-NITROPHENOL'>NPO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j50 OCA], [https://pdbe.org/5j50 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j50 RCSB], [https://www.ebi.ac.uk/pdbsum/5j50 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j50 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum. | ||
| - | + | ==See Also== | |
| - | + | *[[Agglutinin 3D structures|Agglutinin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Artocarpus integer]] |
| - | [[Category: Abhinav | + | [[Category: Large Structures]] |
| - | [[Category: Sharma | + | [[Category: Abhinav KV]] |
| - | [[Category: Surolia | + | [[Category: Sharma K]] |
| + | [[Category: Surolia A]] | ||
| + | [[Category: Vijayan M]] | ||
Current revision
Structure of tetrameric jacalin complexed with Gal beta-(1,3) GalNAc-alpha-OPNP
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