5jhg
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5jhg is ON HOLD Authors: Wang, R., Chen, Q., Zhang, H., Yan, Z., Li, J., Miao, L., Wang, F. Description: Crystal structure of the complex between t...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11== | |
| + | <StructureSection load='5jhg' size='340' side='right'caption='[[5jhg]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5jhg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JHG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jhg OCA], [https://pdbe.org/5jhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jhg RCSB], [https://www.ebi.ac.uk/pdbsum/5jhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jhg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ARHGB_HUMAN ARHGB_HUMAN] May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. | ||
| - | + | ==See Also== | |
| - | + | *[[Rho GTPase 3D structures|Rho GTPase 3D structures]] | |
| - | + | *[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Li | + | [[Category: Homo sapiens]] |
| - | [[Category: Miao | + | [[Category: Large Structures]] |
| - | [[Category: Wang | + | [[Category: Chen Q]] |
| - | [[Category: Wang | + | [[Category: Li J]] |
| - | [[Category: | + | [[Category: Miao L]] |
| - | [[Category: | + | [[Category: Wang F]] |
| + | [[Category: Wang R]] | ||
| + | [[Category: Yan Z]] | ||
| + | [[Category: Zhang H]] | ||
Current revision
Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11
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Categories: Homo sapiens | Large Structures | Chen Q | Li J | Miao L | Wang F | Wang R | Yan Z | Zhang H
