4rau
From Proteopedia
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==crystal structure of RTOFab in complex with human PF4== | ==crystal structure of RTOFab in complex with human PF4== | ||
| - | <StructureSection load='4rau' size='340' side='right' caption='[[4rau]], [[Resolution|resolution]] 3.74Å' scene=''> | + | <StructureSection load='4rau' size='340' side='right'caption='[[4rau]], [[Resolution|resolution]] 3.74Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4rau]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RAU OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4rau]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RAU FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.74Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rau OCA], [https://pdbe.org/4rau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rau RCSB], [https://www.ebi.ac.uk/pdbsum/4rau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rau ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PLF4_HUMAN PLF4_HUMAN] Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.<ref>PMID:7644496</ref> |
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| + | ==See Also== | ||
| + | *[[C-X-C motif chemokine 3D structures|C-X-C motif chemokine 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Cai Z]] |
| - | [[Category: | + | [[Category: Greene MI]] |
| - | [[Category: | + | [[Category: Liu Q]] |
| - | [[Category: | + | [[Category: Zhu Z]] |
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Current revision
crystal structure of RTOFab in complex with human PF4
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Categories: Homo sapiens | Large Structures | Mus musculus | Cai Z | Greene MI | Liu Q | Zhu Z
