1i7o

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[[Image:1i7o.jpg|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF HPCE==
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|PDB= 1i7o |SIZE=350|CAPTION= <scene name='initialview01'>1i7o</scene>, resolution 1.7&Aring;
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<StructureSection load='1i7o' size='340' side='right'caption='[[1i7o]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
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<table><tr><td colspan='2'>[[1i7o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I7O FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i7o OCA], [https://pdbe.org/1i7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i7o RCSB], [https://www.ebi.ac.uk/pdbsum/1i7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i7o ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i7o OCA], [http://www.ebi.ac.uk/pdbsum/1i7o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1i7o RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/HPCE_ECOLX HPCE_ECOLX] Decarboxylates OPET (5-oxo-pent-3-ene-1,2,5-tricarboxylic acid) into HHDD (2-hydroxy-hept-2,4-diene-1,7-dioate) and isomerizes it to OHED (2-oxo-hept-3-ene-1,7-dioate).<ref>PMID:8223600</ref>
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== Evolutionary Conservation ==
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'''CRYSTAL STRUCTURE OF HPCE'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i7/1i7o_consurf.spt"</scriptWhenChecked>
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1I7O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I7O OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i7o ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Dodson, E J.]]
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[[Category: Dodson EJ]]
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[[Category: Namba, K.]]
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[[Category: Namba K]]
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[[Category: Roper, D I.]]
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[[Category: Roper DI]]
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[[Category: Tame, J R.H.]]
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[[Category: Tame JRH]]
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[[Category: bifunctional enzyme]]
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[[Category: decarboxylase]]
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[[Category: isomerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:15:45 2008''
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Current revision

CRYSTAL STRUCTURE OF HPCE

PDB ID 1i7o

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