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4y1y
From Proteopedia
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==Complex of human Galectin-1 and (6OSO3)Galbeta1-3GlcNAc== | ==Complex of human Galectin-1 and (6OSO3)Galbeta1-3GlcNAc== | ||
| - | <StructureSection load='4y1y' size='340' side='right' caption='[[4y1y]], [[Resolution|resolution]] 1.86Å' scene=''> | + | <StructureSection load='4y1y' size='340' side='right'caption='[[4y1y]], [[Resolution|resolution]] 1.86Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4y1y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y1Y OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4y1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y1Y FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6S2:METHYL+2-(ACETYLAMINO)-2-DEOXY-6-O-SULFO-BETA-D-GLUCOPYRANOSIDE'>6S2</scene>, <scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6S2:METHYL+2-(ACETYLAMINO)-2-DEOXY-6-O-SULFO-BETA-D-GLUCOPYRANOSIDE'>6S2</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y1y OCA], [https://pdbe.org/4y1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y1y RCSB], [https://www.ebi.ac.uk/pdbsum/4y1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y1y ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Galectin 3D structures|Galectin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Hsieh TJ]] |
| - | [[Category: | + | [[Category: Lin CH]] |
| - | [[Category: | + | [[Category: Lin HY]] |
| - | + | ||
| - | + | ||
Current revision
Complex of human Galectin-1 and (6OSO3)Galbeta1-3GlcNAc
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