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5int

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==Crystal structure of the C-terminal Domain of Coenzyme A biosynthesis bifunctional protein CoaBC==
==Crystal structure of the C-terminal Domain of Coenzyme A biosynthesis bifunctional protein CoaBC==
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<StructureSection load='5int' size='340' side='right' caption='[[5int]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<StructureSection load='5int' size='340' side='right'caption='[[5int]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5int]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5INT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5INT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5int]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5INT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5INT FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopantothenoylcysteine_decarboxylase Phosphopantothenoylcysteine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.36 4.1.1.36] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5int FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5int OCA], [http://pdbe.org/5int PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5int RCSB], [http://www.ebi.ac.uk/pdbsum/5int PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5int FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5int OCA], [https://pdbe.org/5int PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5int RCSB], [https://www.ebi.ac.uk/pdbsum/5int PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5int ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A6L8Q0G8_BACAN A0A6L8Q0G8_BACAN] Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.[HAMAP-Rule:MF_02225] Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.[RuleBase:RU364078]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Phosphopantothenoylcysteine decarboxylase]]
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[[Category: Bacillus anthracis]]
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[[Category: Structural genomic]]
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[[Category: Large Structures]]
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[[Category: Grimshaw, S]]
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[[Category: Anderson WF]]
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[[Category: Joachimiak, A]]
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[[Category: Grimshaw S]]
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[[Category: Kim, Y]]
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[[Category: Joachimiak A]]
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[[Category: Nocek, B]]
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[[Category: Kim Y]]
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[[Category: Zhou, M]]
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[[Category: Nocek B]]
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[[Category: Carboxy-lyase]]
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[[Category: Zhou M]]
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[[Category: Csgid]]
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[[Category: Lyase]]
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Current revision

Crystal structure of the C-terminal Domain of Coenzyme A biosynthesis bifunctional protein CoaBC

PDB ID 5int

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