5j3e
From Proteopedia
(Difference between revisions)
(New page: ==Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA== <StructureSection load='5j3e' size='340' side='right' caption='5j3e, [[Resolution|resoluti...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA== | ==Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA== | ||
| - | <StructureSection load='5j3e' size='340' side='right' caption='[[5j3e]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='5j3e' size='340' side='right'caption='[[5j3e]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5j3e]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J3E OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5j3e]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J3E FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j3e OCA], [https://pdbe.org/5j3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j3e RCSB], [https://www.ebi.ac.uk/pdbsum/5j3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j3e ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/THYN1_HUMAN THYN1_HUMAN] Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: | + | [[Category: Halabelian L]] |
| - | [[Category: | + | [[Category: Li Y]] |
| - | [[Category: | + | [[Category: Tempel W]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA
| |||||||||||
