4z21

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==Crystal structure of ARNO Sec7==
==Crystal structure of ARNO Sec7==
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<StructureSection load='4z21' size='340' side='right' caption='[[4z21]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='4z21' size='340' side='right'caption='[[4z21]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4z21]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z21 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4z21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z21 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jmi|4jmi]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z21 OCA], [http://pdbe.org/4z21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z21 RCSB], [http://www.ebi.ac.uk/pdbsum/4z21 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z21 OCA], [https://pdbe.org/4z21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z21 RCSB], [https://www.ebi.ac.uk/pdbsum/4z21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z21 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CYH2_HUMAN CYH2_HUMAN]] Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane.<ref>PMID:17398095</ref>
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[https://www.uniprot.org/uniprot/CYH2_HUMAN CYH2_HUMAN] Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane.<ref>PMID:17398095</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Yun, C H]]
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[[Category: Homo sapiens]]
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[[Category: Zhu, S J]]
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[[Category: Large Structures]]
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[[Category: Arno]]
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[[Category: Yun CH]]
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[[Category: Sec7]]
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[[Category: Zhu SJ]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of ARNO Sec7

PDB ID 4z21

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