3jcp
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of yeast 26S proteasome in M2 state derived from Titan dataset== | |
| - | + | <SX load='3jcp' size='340' side='right' viewer='molstar' caption='[[3jcp]], [[Resolution|resolution]] 4.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3jcp]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JCP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.6Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jcp OCA], [https://pdbe.org/3jcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jcp RCSB], [https://www.ebi.ac.uk/pdbsum/3jcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jcp ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PSB6_YEAST PSB6_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Huang XL]] | ||
| + | [[Category: Luan B]] | ||
| + | [[Category: Shi YG]] | ||
| + | [[Category: Wang F]] | ||
| + | [[Category: Wu JP]] | ||
Current revision
Structure of yeast 26S proteasome in M2 state derived from Titan dataset
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