5ilh

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'''Unreleased structure'''
 
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The entry 5ilh is ON HOLD until Paper Publication
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==Tobacco 5-epi-aristolochene synthase with CAPSO buffer molecule and Ca2+ ions==
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<StructureSection load='5ilh' size='340' side='right'caption='[[5ilh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ilh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ILH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ILH FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3CX:(2S)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3CX</scene>, <scene name='pdbligand=3FX:(2R)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3FX</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ilh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ilh OCA], [https://pdbe.org/5ilh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ilh RCSB], [https://www.ebi.ac.uk/pdbsum/5ilh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ilh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Nicotiana tabacum]]
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[[Category: Bowman M]]
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[[Category: Koo HJ]]
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[[Category: Louie GV]]
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[[Category: Noel JP]]
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[[Category: Xu Y]]

Current revision

Tobacco 5-epi-aristolochene synthase with CAPSO buffer molecule and Ca2+ ions

PDB ID 5ilh

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