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5j5t
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==GLK co-crystal structure with aminopyrrolopyrimidine inhibitor== | |
| - | + | <StructureSection load='5j5t' size='340' side='right'caption='[[5j5t]], [[Resolution|resolution]] 2.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5j5t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J5T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6G2:5-[2-(PIPERIDIN-4-YL)-1,3-THIAZOL-5-YL]-3-[(PYRIDIN-4-YL)METHOXY]PYRIDIN-2-AMINE'>6G2</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j5t OCA], [https://pdbe.org/5j5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j5t RCSB], [https://www.ebi.ac.uk/pdbsum/5j5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j5t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/M4K3_HUMAN M4K3_HUMAN] May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.<ref>PMID:9275185</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Marcotte D]] | ||
| + | [[Category: Silvian LF]] | ||
Current revision
GLK co-crystal structure with aminopyrrolopyrimidine inhibitor
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