5jno
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the BD1-NTPR complex from BEND3 and PICH== | |
| - | + | <StructureSection load='5jno' size='340' side='right'caption='[[5jno]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5jno]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JNO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JNO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jno OCA], [https://pdbe.org/5jno PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jno RCSB], [https://www.ebi.ac.uk/pdbsum/5jno PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jno ProSAT]</span></td></tr> |
| - | [[Category: Hickson | + | </table> |
| - | [[Category: Montoya | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/BEND3_HUMAN BEND3_HUMAN] Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (By similarity).[UniProtKB:Q6PAL0]<ref>PMID:21914818</ref> <ref>PMID:26100909</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hickson ID]] | ||
| + | [[Category: Mesa P]] | ||
| + | [[Category: Montoya G]] | ||
| + | [[Category: Pitchai G]] | ||
Current revision
Crystal structure of the BD1-NTPR complex from BEND3 and PICH
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