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1in0

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[[Image:1in0.jpg|left|200px]]
 
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{{Structure
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==YAJQ PROTEIN (HI1034)==
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|PDB= 1in0 |SIZE=350|CAPTION= <scene name='initialview01'>1in0</scene>, resolution 2.14&Aring;
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<StructureSection load='1in0' size='340' side='right'caption='[[1in0]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MMC:METHYL+MERCURY+ION'>MMC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
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<table><tr><td colspan='2'>[[1in0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IN0 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
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|GENE= yajQ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MMC:METHYL+MERCURY+ION'>MMC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1in0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1in0 OCA], [https://pdbe.org/1in0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1in0 RCSB], [https://www.ebi.ac.uk/pdbsum/1in0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1in0 ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1in0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1in0 OCA], [http://www.ebi.ac.uk/pdbsum/1in0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1in0 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Y1034_HAEIN Y1034_HAEIN]
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== Evolutionary Conservation ==
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'''YAJQ PROTEIN (HI1034)'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==Overview==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/in/1in0_consurf.spt"</scriptWhenChecked>
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A hypothetical protein encoded by the gene YajQ of Haemophilus influenzae was selected, as part of a structural genomics project, for X-ray crystallographic structure determination and analysis to assist with the functional assignment. The protein is present in most bacteria, but not in archaea or eukaryotes. The amino acid sequence has no homology to that of other proteins. The YajQ protein was cloned, expressed, and the crystal structure determined at 2.1-A resolution by applying the multiwavelength anomalous dispersion method to a mercury derivative. The polypeptide chain is folded into two domains with identical folding topology. Each domain has a four-stranded antiparallel beta-sheet flanked on one side by two alpha-helices. This structural motif is a characteristic feature of many RNA-binding proteins. The tetrameric structure observed in the crystal suggests a possibility of binding two stretches of double-stranded nucleic acid.
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1IN0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IN0 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1in0 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains., Teplyakov A, Obmolova G, Bir N, Reddy P, Howard AJ, Gilliland GL, J Struct Funct Genomics. 2003;4(1):1-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12943362 12943362]
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</StructureSection>
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Gilliland, G L.]]
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[[Category: Gilliland GL]]
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[[Category: S2F, Structure 2.Function Project.]]
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[[Category: Teplyakov A]]
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[[Category: Teplyakov, A.]]
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[[Category: alpha and beta sandwich]]
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[[Category: s2f]]
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[[Category: structural genomic]]
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[[Category: structure 2 function project]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:21:58 2008''
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Current revision

YAJQ PROTEIN (HI1034)

PDB ID 1in0

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