4x0e

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==Structure of M. tuberculosis nicotinate mono nucleotide adenylyltransferase==
==Structure of M. tuberculosis nicotinate mono nucleotide adenylyltransferase==
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<StructureSection load='4x0e' size='340' side='right' caption='[[4x0e]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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<StructureSection load='4x0e' size='340' side='right'caption='[[4x0e]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4x0e]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X0E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X0E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4x0e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X0E FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nicotinate-nucleotide_adenylyltransferase Nicotinate-nucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.18 2.7.7.18] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x0e OCA], [http://pdbe.org/4x0e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x0e RCSB], [http://www.ebi.ac.uk/pdbsum/4x0e PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x0e OCA], [https://pdbe.org/4x0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x0e RCSB], [https://www.ebi.ac.uk/pdbsum/4x0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x0e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NADD_MYCTU NADD_MYCTU]] Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
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[https://www.uniprot.org/uniprot/NADD_MYCTU NADD_MYCTU] Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Nicotinate-nucleotide adenylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Ostermna, A L]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Zuccola, H J]]
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[[Category: Ostermna AL]]
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[[Category: Enzyme inhibitor]]
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[[Category: Zuccola HJ]]
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[[Category: Transferase]]
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Structure of M. tuberculosis nicotinate mono nucleotide adenylyltransferase

PDB ID 4x0e

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