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5g49
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5g49 is ON HOLD until Paper Publication Authors: Gnesutta, N., Saad, D., Chaves-Sanjuan, A., Mantovani, R., Nardini, M. Description: Crystal struct...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the Arabodopsis thaliana histone-fold dimer L1L NF-YC3== | |
| + | <StructureSection load='5g49' size='340' side='right'caption='[[5g49]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5g49]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G49 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G49 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g49 OCA], [https://pdbe.org/5g49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g49 RCSB], [https://www.ebi.ac.uk/pdbsum/5g49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g49 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NFYB6_ARATH NFYB6_ARATH] Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. Plays a role in the regulation of the embryogenesis. Involved in the abscisic acid (ABA) signaling pathway.<ref>PMID:12509518</ref> <ref>PMID:17322342</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The structural analysis of the L1L/NF-YC3 histone dimer from A. thaliana shows that it can trimerize and bind to the CCAAT box. Specific sequence and structural features at the protein/DNA interface, in particular the presence of a Asp-His pair, help explain the molecular mechanisms of LEC1/L1L activity as a bona fide mammalian-like NF-YB. | ||
| - | + | Crystal structure of the Arabidopsis thaliana L1L/NF-YC3 histone-fold dimer reveals specificities of the LEC1 family of NF-Y subunits in plants.,Gnesutta N, Saad D, Chaves-Sanjuan A, Mantovani R, Nardini M Mol Plant. 2016 Nov 18. pii: S1674-2052(16)30276-3. doi:, 10.1016/j.molp.2016.11.006. PMID:27871811<ref>PMID:27871811</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Chaves-Sanjuan | + | <div class="pdbe-citations 5g49" style="background-color:#fffaf0;"></div> |
| - | [[Category: Gnesutta | + | |
| - | [[Category: | + | ==See Also== |
| - | [[Category: | + | *[[Nuclear transcription factor Y|Nuclear transcription factor Y]] |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arabidopsis thaliana]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chaves-Sanjuan A]] | ||
| + | [[Category: Gnesutta N]] | ||
| + | [[Category: Mantovani R]] | ||
| + | [[Category: Nardini M]] | ||
| + | [[Category: Saad D]] | ||
Current revision
Crystal structure of the Arabodopsis thaliana histone-fold dimer L1L NF-YC3
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